By David I. Graham, James A.R. Nicoll, Ian Bone (Eds.)
Advent to Neuropathology 3Ed continues to be an introductory textual content, yet extra medical fabric has been brought to make it appropriate to neurologists and a few psychiatrists, in addition to pathologists. This includes the addition of small quantities of textual content all through, plus neuroimages, together with sensible MRI, that is in color. furthermore, the textual content has been up-to-date all through with a brand new group of contributing authors.
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Extra resources for Adams & Graham's Introduction to Neuropathology
Here the pupillary light reflex is retained despite the absence of any conscious perception of light. This may occur in a patient who has already sustained an occipital infarct from posterior cerebral artery 29 occlusion who then suffers a similar event on the opposite side. Simultaneous occipital infarction may be the consequence of distal basilar artery occlusion, transtentorial herniation with compression of the posterior cerebral arteries, or may occur as a result of a hypoxic ischemic event, such as status asthmaticus.
When impairment of sensation is associated with this pain, the term anesthesia dolorosa is used. Thalamic pain and thalamic syndromes are rare, and although they occur with tumors they are usually more indicative of cerebrovascular disease, in particular disease affecting the small perforating blood vessels. Whilst vascular disease is the commonest thalamic pathology, involvement is seen in many conditions such as cerebral palsy, head injury, infections, variant CJD (selectively affecting the pulvinar and dorsomedial nucleus) and frontotemporal dementia.
Prolactin, growth hormone and adrenocorticotrophic hormone (ACTH) in tissue that has been fixed in formalin and embedded in paraffin wax. Surgical biopsies are often small, and it is sometimes difficult to distinguish between metastatic carcinoma and some types of malignant neuroepithelial tumor. Antibodies for identifying metastatic carcinoma, such as the cytokeratins and epithelial membrane antigen, may aid in establishing the diagnosis. g. anti-thyroid transcription factor (anti-TTF1) for an origin in bronchus, thyroglobulin for an origin in thyroid, and melanan A or HMB-45 for melanoma.