Download e-book for kindle: Biggles - Air Detective by W. E. Johns

By W. E. Johns

This includes seven brief tales. they're all Air Police tales aside from the final one, that's a moment international conflict tale. those are as follows:-

THE CASE OF THE BLACK SHEEP

An ex-RAF Officer is utilizing his plane to smuggle nylons into the united kingdom, deciding upon them up from a ship.

THE CASE OF THE vacationing SULTAN

A infamous US gangster is making plans to assault a Sultan's airplane with the intention to scouse borrow his diamonds.

THE CASE OF THE UNREGISTERED OPERATOR

Biggles is going to felony for you to discover an unlawful air transportation operation for criminals.

THE CASE OF THE WOUNDED AGENT

Biggles is shipped on a different project to save lots of a undercover agent, and his info, from Bulgaria.

THE CASE OF the bright PUPIL

An first-class flying student, who already is aware the best way to fly, is utilizing his solo flights for unlawful reasons.

THE CASE OF THE MURDERED APPRENTICE

Biggles uncovers a smuggling operation from Holland whilst investigating why a guy was once murdered.

THE CASE OF THE STOLEN AIRCRAFT

A guy who has designed a brand new airplane is stealing airplane for the aviation gasoline they contain.

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1976). In general, there is a similar amount and distribution of AR in male and female genital skin (Griffin et al. 1976; Mowszowicz et al. 1981). 41 42 C. A. S Ontogeny of AR expression in fetal and postnatal life Expression of AR in the human fetus is present even prior to the onset of testicular androgen secretion and androgen binding is greater in genital than non-genital tissues during weeks 8-22 of gestation (Sultan et al. 1980, 1982). There is a marked similarity in distribution and intensity of AR staining in the external genitalia of male and female fetuses at 18-22 weeks gestation (Kalloo et al.

1991). 3 Androgen receptor protein The AR is a member of the group of four closely-related steroid receptors that also includes the progesterone receptor (PR), glucocorticoid receptor 37 38 c. A. Quigley (GR) and mineralocorticoid receptor (MR) - sometimes referred to as the "GR-like" receptors. These four receptors, related by their sequence homology and also by their ability to activate target gene transcription via the same HRE, comprise a sub-group of the larger and more diverse family of nuclear transcription factors that includes the estrogen receptor (ER), thyroid hormone receptors (TRa and TRf3), vitamin D receptor (VDR), retinoic acid receptor (RAR), retinoid X receptor (RXR), and a number of related receptors for which ligands have not yet been identified in many cases.

Functional domains and structural organization of the AR .. The amino-terminal domain . . . . . . . . . . The DNA-binding domain (DBD) . . . . . . . . . . . . The nuclear targeting signal and hinge region . . . . The ligand-binding domain . . . . 4 Tissue distribution of AR . . . . 7 . Molecular mechanisms of AR action . . . Ligand binding ... . . . . . . . . Phosphorylation ... .. . . . . . . . Nuclear localization .. . .. . . . .

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