Cell Biology of the B Cell Receptor by Hidde L Ploegh PDF

By Hidde L Ploegh

Advances in Immunology, a customary and hugely revered e-book, provides present advancements in addition to accomplished reports in immunology. Articles handle the big variety of themes that include immunology, together with molecular and mobile activation mechanisms, phylogeny and molecular evolution, and medical modalities. Edited and authored by way of the main scientists within the box, every one quantity presents up to date details and instructions for the future.

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* Contributions from prime specialists * Informs and updates on the entire most modern advancements within the box

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Et al. (2013). A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi. The Journal of Experimental Medicine, 210(1), 59–70. 20121801. , Van Etten, R. , et al. (2014). Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia. Nature Immunology, 15, 294–304. 2821. Jun, J. , Wilson, L. , Vinuesa, C. , Miosge, L. , et al. (2003). Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

Proceedings of the National Academy of Sciences of the United States of America, 111(4), 1497–1502. 1314121111. , & Miller, R. A. (1991). Autoantibody activity of immunoglobulins isolated from B-cell follicular lymphomas. Blood, 78(3), 581–585. , et al. (2013). Integrin CD11b negatively regulates BCR signalling to maintain autoreactive B cell tolerance. Nature Communications, 4, 2813. 1038/ncomms3813. Ding, B. , Yu, J. , Yu, R. , Mendez, L. , et al. (2008). Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas.

Et al. (2013). The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling. Immunity, 38(3), 461–474. 019. McGaha, T. , & Ravetch, J. V. (2005). Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science, 307(5709), 590–593. 1105160. , & Wardemann, H. (2008). B-cell tolerance checkpoints in health and autoimmunity. Current Opinion in Immunology, 20(6), 632–638. 001. Merrell, K. , Benschop, R. , Gauld, S. , Wysocki, L.

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