By Christian Lauritzen, John W. W. Studd
The main updated and entire overseas paintings on menopause and postmenopause, this article has been assembled via well-known opinion-leaders all through Europe. present administration of the Menopause explores what menopause is precisely and its have an effect on on assorted platforms within the physique, however it additionally discusses the non-medical facets of the situation, comparable to women's reactions to creating a transition right into a new part of existence. The specialists totally clarify the scientific matters, addressing controversies, equivalent to that over where of HRT in remedy of menopausal sufferers, head-on. This quantity is perfect for gynecologists, common practitioners, and scholars in these fields.
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Extra info for Current Management of the Menopause
3. Beral V. Million Women Study Collaborators. Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet 2003; 362: 419–27. 4. Lagro-Jannsen T, Rosser WW, van Weel C. Breast cancer and hormone-replacement therapy; up to general practice to pick up the pieces. Lancet 2003; 362:414–15. 5. Studd J. —a response to WHI and MWS. Maturitas 2003; 46:95–7. 6. Hays J, Ockene JK, Brunner RL et al, Women’s Health Initiative Investigators. Effects of estrogen plus progestin on health-related quality of life.
Perimenopausal and post-menopausal patients with vasomotor symptoms should be given either oral or transdermal estradiol with cyclical progestogen for endometrial protection. 5. The usual duration of progestogen is 14 days but if the extra risk to the breasts from progestogen is confirmed it would be sensible to reduce the duration to 7–10 days. A shortened course is useful in women with progestogen intolerance. 6. Patients may wish to avoid bleeding by using low dose estrogen and progestogen or have a Mirena IUS (Mirena intrauterine system) inserted or take tibolone.
11. Douglas P, Poppas A. Determinants and management of cardiovascular risk in women. Wellesley (MA): Up To Date, 2002. 12. Peeters A, Mamun AA, Willekens F, Bonneux L. A cardiovascular life history, a life course analysis of the original Framingham Heart Study cohort. Eur Heart J 2002; 23:458–66. 13. Menhem K, Dotevall A, Wilhelmsen L, Rosengren A. Social gradients in cardiovascular risk factors and symptoms of Swedish men and women: the Goteborg Monica Study 1995. J Cardiovasc Risk 2000; 7:359–68.