By Vijay Kumar Thakur
Polymers are essentially the most attention-grabbing fabrics of the current period discovering their functions in virtually each points of lifestyles. Polymers are both without delay to be had in nature or are chemically synthesized and used based upon the unique applications.Advances in polymer technology and the creation of recent polymers have led to the numerous improvement of polymers with special properties. other kinds of polymers were and may be one of many key in numerous purposes in lots of of the complex pharmaceutical learn being performed over the globe.
This 4-partset of books comprises accurately referenced chapters, emphasizing other kinds of polymers with easy basics and practicality for program in diversified pharmaceutical applied sciences. The volumes goal at explaining fundamentals of polymers established fabrics from diversified assets and their chemistry in addition to sensible functions which current a destiny path within the pharmaceutical undefined. every one quantity supply deep perception into the topic being treated.
Volume 1: constitution and Chemistry
Volume 2: Processing and Applications
Volume three: Biodegradable Polymers
Volume four: Bioactive and suitable Synthetic/Hybrid Polymers
Read Online or Download Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry Volume 1 PDF
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Additional info for Handbook of Polymers for Pharmaceutical Technologies, Structure and Chemistry Volume 1
The delivery of antimicrobial therapy directly to the periodontal pockets has the significance of putting additional drugs at the target site, while minimizing the risk of exposure of the body to the drug . 6 Gastrointestinal Drug Delivery The calcium chloride crosslinked gellan formulations were evaluated as a gastroretentive drug delivery system for controlled release of the drug ornidazole in order to treat gastric ulcers associated with H. pylori . Their observations showed that the concentration of gellan in the prepared formulation significantly affected the in-vitro release profile of the drug.
Handbook of Polymers for Pharmaceutical Technologies, (23–50) © 2015 Scrivener Publishing LLC 23 24 Handbook of Polymers for Pharmaceutical Technologies of development and manufacture as well as from the process control and scale-up points of view [1,6–9]. The most prevalent are hydrophilic matrices, which most often provide a desirable drug release profile, are cost effective and have a broad regulatory acceptance [5,10–12]. The majority of commercially available matrix formulations are in the form of tablets, and although developing them may initially seem simple, the formulation scientist is required to consider a number of variables that influence drug release, as well as the manufacturing and processing of these tablets.
27. W. A. Bristol, Acute oral toxicity study in rats, Hazelton Laboratories America, Inc. Vienna, VA, USA, 1980. 28. B. L. Keenan, R. J. , Vienna, VA, USA, 1980. 29. M. P. Kumar, B. C. Pharmacy and B. Karnataka, Natural polysaccharide hydrogels as novel excipients for modified drug delivery systems : A review, International Journal of ChemTech Research, 2: 509–525, 2010. 30. J. Silva-Correia, A. F. M. Oliveira, L. L. Reis, Rheological and mechanical properties of acellular and cell-laden methacrylated gellan gum hydrogels, J.