Download e-book for iPad: Monophasic Action Potentials: Basics and Clinical by S. Bertil Olsson, Shiwen Yuan (auth.), Michael R. Franz

By S. Bertil Olsson, Shiwen Yuan (auth.), Michael R. Franz M.D., Ph.D., Priv.-Doz. Dr. Claus Schmitt, Dr. Bernhard Zrenner (eds.)

Over the final 20 years monophasic motion capability (MAP) recording has matured right into a strategy that offers a hyperlink among uncomplicated and medical electrophysiology. foreign specialists current interesting information on MAP recording concepts, the mechanism and interpretation of MAPs, and novel facets of repolarization-related arrhythmias.

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Additional info for Monophasic Action Potentials: Basics and Clinical Application

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Cardiovasc Res 22:255-264 22. Brorson L, Olsson SB (1976) Atrial repolarization in healthy males. Studies with programmed stimulation and monophasic action potential recordings. Acta Med Scand 199:447-454 23. Franz MR, Kirchhof PF, Fabritz CL, Zabel M (1995) Computer analysis of monophasic action potentials: manual validation and clinically pertinent applications. Pacing Clin ElectrophysioI18:1666-1678 24. Koller B, Franz MR (1994) New classification of moricizine and propafenone based on electrophysiologic and electrocardiographic data from isolated rabbit heart.

Epicardial MAP Recording Probes MAPs can be recorded from the human epicardium using special spring-loaded contact electrode probes [9]. Figure 5 shows a probe designed for use in the cardiac operating room. Two nonpolarizable electrodes are mounted on a flat ribbon in such a configuration that only the exploring tip electrode comes in direct contact Fig. 5. Epicardial MAP electrode. MAP contact electrode probe for mapping epicardial repolarization wave forms in the cardiac operating room 28 MICHAEL R.

The isolated perfused heart preparation and the MAP electrode array can be immersed within a perfusate-filled chamber whose walls are flanked by ECG electrodes in approximate Einthoven and Wilson configurations. This has helped to examine the correlation between ventricular repolarization at the myocardial tissue level and a 12-lead volume conducted ECG which resembles the surface ECG [16]. , by predicting the surface ECG from myocardial voltage generators [17] and to understand the electrocardiographic mechanism of "torsade de pointes" arrhythmias on the basis of local myocardial repolarization abnormalities [17].

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