Download e-book for kindle: Neurochemical Correlates of Cerebral Ischemia by Nicolas G. Bazan, Pierre Braquet, Myron D. Ginsberg

By Nicolas G. Bazan, Pierre Braquet, Myron D. Ginsberg

During this well timed quantity, eminent researchers supply special insurance of the suitable functionality of neurochemical correlates to cerebral ischemia in addition to their pathophysiological importance.

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Additional resources for Neurochemical Correlates of Cerebral Ischemia

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Three samples of contralateral cortex from each brain were assayed routinely and then averaged to give the value shown for cortical area no. 1. The sites for the remaining samples were dissected from the ipsilateral cortex and are presented in Figure 3. 05) were determined by analysis of variance (ANOVA) with Duncan's method performed for individual comparisons. 3. Localization of Focal and Perifocal Sites by Using Neutral Red To minimize the problems created by sampling tissue on the basis of anatomical landmarks, 2 ml of a 2% solution of the weak base chromophore neutral red (NR) was slowly infused into rats approximately 30 minutes prior to in situ fixation of the brain.

Reversible Occlusion Models Location of occlusiona Method of occlusion; straina Proximal to RB Snare; SD Proximal to LSB Endovascular occlusion ICA, ACA, and MCA; SD Photocoagulation of CCA with acute recanalization; SD Coagulation of distal MCA plus snare ligation of CCS; W, F, SHR Distal to RB Distal RB Commentsa References Temporary ischemia, direct reperfusion, determination of ischemic edema Temporary occlusion of MCA without craniotomy Shigeno et al. (1985) Occlusion without violating dura; direct reperfusion Nakayama et al.

And Lassen, N. , 1977, Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia, Stroke 8:51-57. Bederson,1. , Pitts, L. , Nishimura, M. , Davis, R. , 1986, Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination, Stroke 17:472-476. Bielenberg, G. , 1987, Effects of calcium entry blocker emopamil on postischemic energy metabolism of the isolated perfused rat brain, 1. Cereb. Blood Flow Metab. 7:489-496. , Engell, H.

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